The Port Macquarie public are invited to strip down to their undies for a fun run along the breakwall to raise awareness of a serious condition.
Neurofibromatosis (NF) is a condition which causes tumours to grow throughout the body. There is no cure and limited treatment available.
Port Macquarie resident Peter Kirkpatrick would NF like to be a condition of the past rather than having to constantly worry about the future.
His nine-year-old daughter Emily was diagnosed with NF1 when she was 10-months-old.
Mr Kirkpatrick has organised a Cupid's Undie Run in Port Macquarie at 10am on Sunday, February 19.
It is an event held across Australia in February to raise funds and awareness for the Children's Tumour Foundation of Australia and NF.
Mr Kirkpatrick said he hoped people would show their support by stripping down to their undies and running, walking, skipping or hopping from the southern Town Beach Kiosk to the Town Green.
Participants just need to show up on the day and will finish on the riverside grass in front of The Beach House.
Mr Kirkpatrick said their family was absolutely devastated when they discovered Emily had a tumour on her leg when she was 10-months-old.
When Emily was six-years-old her leg was removed through amputation and she now walks with the aid of a prosthetic leg.
She has also been diagnosed with two brain tumours and epilepsy.
In Port Macquarie the Kirkpatrick family connected with Jesse Fisher who also has NF and became close with his family.
Emily has been recognised by the Children's Tumour Foundation of Australia as an NF Hero for sharing her story.
NF can lead to blindness, bone abnormalities, cancer deafness and learning difficulties.
Mr Kirkpatrick said the Children's Tumour Foundation of Australia help families like theirs by providing funding for specialists, research and camps.