A lifeguard, the Department of Primary Industries and Marine Rescue Port Macquarie came to man's rescue after waves knocked him out of his boat on a run-out tide about 11.30am.

Marine Rescue Port Macquarie unit commander Greg Davies said the DPI boat picked up the man about 300 metres out to sea.

Marine Rescue Port Macquarie responded by jet ski and a lifeguard paddled out to the scene.

Rescuers took control of the boat and brought it back to the Marine Rescue shed.

The man, who had a gash to his head, was brought back to the Town Green and was subsequently taken to hospital.

"It was a great job by all involved working together to save a life," Mr Davies said.

Mid North Coast lifeguard coordinator James Turnham acknowledged the combined efforts of rescuers.

The man was wearing an inflatable jacket at the time of the incident.

"If he didn't have that inflatable jacket on, it could have been a different story," Mr Turnham said.