Police appeal for any information on missing Port Macquarie man Patrick Cowan.

Still missing: Patrick Cowan, 34, of Port Macquarie is missing. Photo: NSW Police

Still missing: Patrick Cowan, 34, of Port Macquarie is missing. Photo: NSW Police

Police reinforce their appeal for information to help locate a man missing in Port Macquarie.

Patrick Cowan, aged 34, left his home in Port Macquarie early on Monday, October 9 and has not been seen since.

Police were contacted and about 7.30am his vehicle, a blue Toyota Rav4, was located unattended on Matthew Flinders Drive.

An extensive search of the area over several days involved numerous agencies including Marine Rescue, SES, Police Dog Unit and PolAir.

Police and his family have grave concerns for his welfare.

Anyone with information on his whereabouts is urged to contact Port Macquarie Police immediately on 6583 0199.